Conference

Opening Conference for Mathematical Challenges in Brain Mechanics

Project illustration of a sleeping man and a brain map.

This conference is organised by the CAS project "Mathematical Challenges in Brain Mechanics", led by PIs Kent-Andre Mardal (University of Oslo) and Jan Martin Nordbotten (University of Bergen).

Provisional Programme (subject to change)
 

Day 1, Wednesday 20 August

08:30-09:00      
Arrival & coffee

09:00-09:10
Welcome and opening remarks by Kent-Andre Mardal and Jan Martin Nordbotten

09:10-09:20
Official opening by Bjørn Jamtveit, pro-rector at the University of Oslo

Session 1
Session chair: Kent-Andre Mardal

09:20-10:00
Maiken Nedergaard (University of Rochester, US/University of Copenhagen, DK): Brain fluid transport

10:00-10:40
Per Kristian Eide (University of Oslo, NO/Rikshospitalet, NO): Extra-vascular solute transport in human brain

10:40-11:00
Coffee

Session 2
Session chair: Jan M. Nordbotten

11:00-11:40
Alfio Maria Quarteroni (MOX, Politecnico of Milan, IT): Scientific machine learning

11:40-12:20
Huifang Wang (INSERM, Aix-Marseille Université, FR): Virtual brain twins: from basic neuroscience to clinical use

12:20-13:20
Lunch

Session 3
Session chair: Kent-Andre Mardal

13:20-14:00
Arvid Lundervold (University of Bergen, NO): Precision segmentation of glioma growth

14:00-14:40
Kaja Nordengen (Rikshospitalet, NO): Glymphatics in Parkinson's disease

14:40-15:00
Coffee

Session 4
Session chair: Jan M. Nordbotten

15:00-15:40
Marie Rognes (Simula Research lab, Oslo, NO): Brain membranes and vasculature: a computational mathematics tale of dimensional gaps

15:40-16:20
Poul Jørgen Jennum (Danish Center for Sleep Medicine, Rigshospitalet, DK): Use of AI to understand sleep-wake mechanism in neurodegenerative disorders

16:20-18:30
Evening break

18:30-19:00
Reception

19:00-22:00
Dinner

 

Day 2, Thursday 21 August

08:30-09:00      
Arrival & coffee

Session 1
Session chair: Marie Rognes

09:00-09:40
Peter Bork (University of Copenhagen, DK): Identifying the main mechanisms in brain fluid flow using minimal modeling 

09:40-10:20
Alexandre Poulain (Université de Lille, FR): Modeling glioma-induced impairments on the glymphatic system

10:20-10:40
Coffee

Session 2
Session chair: Erik Hanson

10:40-11:20
Douglas H. Kelley (University of Rochester, US): Mapping deep brain fluid flow in vivo with machine learning

11:20-12:00
Antonio Iorio (School of Life Sciences, University of Dundee, Dundee, UK): Fluid flow and amyloid transport and aggregation in the brain interstitial space

12:00-13:00
Lunch

Session 3
Session chair: Paolo Zunino

13:00-13:40
Alberto Girelli (Catholic University of Milan, IT): Mathematical models of the lymph flow: analysis and simulations

13:40-14:20
Wahbi K. El-bouri (University of Liverpool, UK): Multi-scale modelling of the cerebro-retinal circulation

14:20-15:00
Erlend Hodneland (University of Bergen, NO): From vessels to vertices: graph-based representations of cerebral blood flow

15:00-15:20
Coffee

Session 4
Session chair: Xue-Cheng Tai

15:20-16:00
Paolo Zunino (MOX, Politecnico of Milan, IT): Multi-physics models of the vascular microenvironment: A journey from mathematics to computational oncology

16:00-16:40
Enrico Facca (University of Padova, IT): Reconstruction of the brain blood vessels network from time-of-flight MRA

16:40-17:00
Evening break and doors close

 

Day 3, Friday 22 August

08:30-09:00      
Arrival & coffee

Session 1
Session chair: Trond Kvamsdal

09:00-09:40
Ricardo Nochetto (University of Maryland, US): Monotone two-scale methods for a class of integro-differential operators

09:40-10:20
Luca Formaggia (MOX, Politecnico of Milan, IT): Reduced order models for mixed-dimensional fluid flow: combining stable finite volume methods with machine learning

10:20-10:40
Coffee

Session 2
Session chair: Ricardo Ruiz-Baier

10:40-11:20
Daniel Førland Holmen (University of Bergen, NO): Modeling and approximation theory for mixed-dimensional problems
Andreas Solheim (Simula Research Lab, Oslo, NO): The role of brain geometry in glymphatic modeling

11:20-12:00
Abner J. Salgado (University of Tennessee, US): Asymptotic compatibility of parameterized optimal design problems

12:00-13:00
Lunch

Session 3
Session chair: Ivan Yotov

13:00-13:40
Ricardo Ruiz-Baier (Monash University, AU): A priori and a posteriori error bounds for the fully mixed FEM formulation of poroelasticity with stress-dependent permeability

13:40-14:20
Luca Heltai (University of Pisa, IT): Mixed dimensional problems on non-matching grids at the exascale: solutions, challenges, and perspectives

14:20-15:00
Miroslav Kuchta (Simula Research Lab, Oslo, NO): Preconditioning the brain

15:00-15:20
Coffee

Session 4
Session chair: Mats Larson

15:20-16:00
Ivan Yotov (University of Pittsburgh, US): Mathematical and numerical modeling of fluid poroelastic structure interaction

16:00-16:40
Espen Sande (Simula Research Lab, Oslo, NO): Preconditioning the Stokes problem on slender domains

16:40-17:15
Closing words and doors close